This series mixer is asymmetrically cantilevered with single helix. The helix will make self-rotation and the screw arm will revolve to complete convecfion, cuting and diffusing to achieve the purpose of mixing. Vertical Blender can be applied in the mixture, reaction, drying and cooling of powder to powder (S-S) powder to liquid (S-L), and liquid to liquid (L-L) in the chemical, medicine, pesficide, dye, petroleum, metallurgy and construction material fields.